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Cutting-edge research, from fundamental to applied research

Research in Haut-Normandie encompasses a wide range of skills from fundamental research through to applied development in the areas of formulation and industrial processes. It centres around the universities of Rouen and Le Havre, with some twenty companies dedicated to the fields of therapeutic chemistry, biology and imaging, amongst others. These teams are interconnected within the major research networks.

The Institute of Biomedical Research and Innovation of Haute-Normandie (IRIB) and the Organic and Analytical Chemistry Laboratory (COBRA) have a prestigious reputation. With the support of major label research platforms in the fields of imaging (PRIMACEN), proteomics (PISSARO), and structural analysis (C2Iorga) for example, these structures also have access to extremely efficient knowledge tools that include a tumour samples library and a biological resource centre, for example. Research activities also extend as far as patients, with the University Hospital research campus in Rouen, which has a clinical investigation centre and is equipped with the latest medical imaging equipment.

Public/private cooperation

Research in the Haute-Normandie region has given rise to numerous instances of cooperation between the public and private sectors, with major producers in the cosmetics, chemistry and pharmaceuticals sectors, and has led to the creation of a mixed research team. Several spin-off companies have been created on the basis of research results obtained in Normandy.

The Major Chemistry-Biology-Health Research Network (GRR CBS)

Research in Haute-Normandie is organised via the Major Chemistry-Biology-Health Research Network (GRR CBS) offering a continuum of chemistry extending through biology to the medical domain, with the development of many forms of interregional cooperation.

The key components are as follows:

The IRIB, a joint research structure for high-level biomedical research focusing on understanding of the physiopathology of diseases and the development of new diagnostic and therapeutic tools as a result of the joint efforts of clinicians, biologists and chemists at the University of Rouen.

This organisation brings together 16 research units, a Clinical Investigation Centre and 10 joint services and platforms, representing over 360 researchers.

The 3 key areas of research carried out here are:

  • Neurosciences (neuronal and neuroendocrine differentiation, neurosecretion; neuroendocrine tumours and glial tumours; Alzheimer's disease; perinatal neurological handicaps).
  • The Genetics-Cancer-Immunology domain (genetics of cancer and lymphomas; Micro-environment - cancer and reproduction; auto-immune muscle, joint and skin diseases).
  • The Cardiovascular-nutrition domain (cardiac failure; endothelial diseases; nutritional disorders) with marked cross-sectional efforts in terms of translational research and of diagnostic and therapeutic innovation.

The Haute-Normandie IRIB also includes the LARC Neurosciences network, an international associative structure that groups together the majority of neurobiology laboratories in the north-west of France and border regions. The LARC-Neurosciences network is aiming to create a Neuropole on a European scale with targeted activities in two particular major areas:

  • "Neuroendocrinology and new neuropeptides"
  • "Ageing - Neurodegenerative diseases - Ischaemia - Neuronal death".

The CRUNCh network (University of Normandy Chemistry Research Centre), an interregional network comprising a group of 7 chemistry laboratories (3 UMR CNRS, 1 UMR CEA, 3 EA), with over 160 researchers and research teaching staff. In response to the challenges of pharmacy and chemistry, this network is currently developing interregional projects focusing on 7 major topics: eco-compatible chemistry, chemistry for analysis, chemistry for health, heterochemistry, functional organometallic compounds, chemistry and physical chemistry of polymers and 'smart' polymers.

The Health Safety Network, whose primary activities centre upon health and environmental safety in terms of microbiology and toxicology. In particular, they concern the study of alternative means of antimicrobial combat for use in chemical processes, the creation of new domains based upon innovative decontamination processes for biotic and abiotic surfaces, and the creation of a technical platform for alternative toxicology testing in place of animal experimentation.

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